In vivo antioxidant assessment of two antimalarial plants–Allamamda cathartica and Bixa orellana

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Antimalarial evaluation of the chemical constituents of hairy root culture of Bixa orellana L.

Over 216 million malaria cases are reported annually worldwide and about a third of these cases, primarily children under the age of five years old, will not survive the infection. Despite this significant world health impact, only a limited number of therapeutic agents are currently available. The lack of scaffold diversity poses a threat in the event that multi-drug-resistant strains emerge. ...

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Chemical constituents and antihistamine activity of Bixa orellana leaf extract

BACKGROUND Bixa orellana L. has been traditionally used in Central and South America to treat a number of ailments, including internal inflammation, and in other tropical countries like Malaysia as treatment for gastric ulcers and stomach discomfort. The current study aimed to determine the major chemical constituents of the aqueous extract of B. orellana (AEBO) and to evaluate the antihistamin...

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Hypoglycaemic activity of Bixa orellana extract in the dog.

In West Indian folklore, a variety of plants are used for medicinal purposes. One such plant, Bixa orellana (annatto), is commonly used in the treatment of diabetes mellitus. Preliminary studies have shown that a crude annatto seed extract exhibited either glucose lowering or hyperglycaemia-inducing activity depending on how it was further manipulated. This present investigation sought to deter...

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Diuretic activity of Bixa orellana Linn. leaf extracts

The present investigation was aimed at investigating the diuretic activity of Bixa orellana Linn. leaves. The dried leaf powder was subjected to successive Soxhlet extraction with petroleum ether, chloroform, ethyl acetate, methanol and water. Among these, petroleum ether, methanolic and aqueous extracts were investigated for diuretic activity in Wistar rats using standard methods. The diuretic...

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ژورنال

عنوان ژورنال: Asian Pacific Journal of Tropical Biomedicine

سال: 2013

ISSN: 2221-1691

DOI: 10.1016/s2221-1691(13)60082-9